Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine nail changes Chloroquine po 300 mg daily Not for administration with other drugs that have potential to prolong QT interval; hydroxychloroquine prolongs QT interval; ventricular arrhythmias and torsades de pointes reported in patients taking hydroxychloroquine Skeletal muscle myopathy or neuropathy leading to progressive weakness and atrophy of proximal muscle groups. Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Clin Pharmacokinet. 1983 May-Jun;83253-62. Pharmacokinetic drug interactions with propranolol. Wood AJ, Feely J. Propranolol is widely used in clinical practice and is frequently administered along with other drugs. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Propranolol interactions with hydroxychloroquine Propranolol hydrochloride and Vitamins drug interactions., Propranolol Oral Route Side Effects - Mayo Clinic Hydroxychloroquine treats what autoimmune diseasesChloroquine tablets lloydsChloroquine alcohol Dosage must be determined by individual titration. Usual propranolol 40 mg/hydrochlorothiazide 25 mg PO q12hr. For total daily propranolol doses 160 mg, combination is not appropriate; use would lead to excessive thiazide dose. Inderide propranolol/hydrochlorothiazide dosing.. Pharmacokinetic drug interactions with propranolol.. Propranolol oral and chloroquine Drug Interactions - RxList. Drug interactions are reported among people who take Propranolol hydrochloride and Plaquenil together. This study is created by eHealthMe based on reports of 6 people who take Propranolol hydrochloride and Plaquenil from Food and Drug Administration FDA, and is updated regularly. eHealthMe is the source of postmarketing drug monitoring. Propranolol slightly to moderately increases the exposure to rizatriptan. Manufacturer advises adjust rizatriptan dose and separate administration by at least 2 hours. Severity of interaction CYP2D6 inhibitors, such as hydroxychloroquine, could theoretically impair propranolol metabolism; the clinical significance of such interactions is unknown. Hydrocodone Moderate Concomitant use of hydrocodone with hydroxychloroquine may increase hydrocodone plasma concentrations and prolong opioid adverse reactions, including hypotension, respiratory depression, profound sedation, coma, and death.