Chloroquine sulphate chronic discoid lupus erythematosus

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    Chloroquine sulphate chronic discoid lupus erythematosus

    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. -Each dose should be taken with a meal or a glass of milk.

    Difference between plaquenil and hydroxychloroquine Chloroquine retinopathy

    These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. Hydroxychloroquine is the drug of choice when a systemic agent is needed for discoid lupus erythematosus DLE. Chloroquine is second-line antimalarial therapy. Chloroquine and hydroxychloroquine should not be used in combination due to the increased risk of ocular toxicity. Cutaneous lupus erythematosus comprises a range of dermatologic manifestations, including acute cutaneous lupus erythematosus, subacute cutaneous lupus erythematosus, and chronic cutaneous lupus erythematosus. The ACR criteria, which include four cutaneous signs, may lead to overdiagnosis of SLE in patients with predominantly cutaneous disease.

    -Concomitant therapy with an 8-aminoquinoline drug is necessary for the radical cure of vivax and malariae malaria. Use: Malaria prophylaxis Acute attack: 800 mg (620 mg base) orally followed in 6 to 8 hours by 400 mg (310 mg base), then 400 mg (310 mg base) once a day for 2 consecutive days; alternatively, a single dose of 800 mg (620 mg base) has also been effective Alternate dosing based on body weight: A total dose representing 25 mg/kg is administered in 3 days, as follows: First dose: 10 mg base/kg (not to exceed 620 mg base) orally Second dose: 5 mg base/kg (not to exceed 310 mg base) orally 6 hours after first dose Third dose: 5 mg base/kg orally 18 hours after second dose Fourth dose: 5 mg base/kg orally 24 hours after third dose Comments: -Each dose should be taken with a meal or a glass of milk.

    Chloroquine sulphate chronic discoid lupus erythematosus

    Hydroxychloroquine Dosage Guide with Precautions -, Discoid Lupus Erythematosus Medication Antimalarial.

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  4. Eighteen cases of chronic discoid lupus erythematosus were treated with chloroquine sulphate by mouth. The results are tabulated and discussed. It is considered that chloroquine sulphate is as effi-cient a form of palliative therapy as any previously used, though not as yet the answer for the chronic disease. There is still a place for CO2 snow treatment where there is a single discoid lesion.

    • Cutaneous Lupus Erythematosus Diagnosis and treatment.
    • Hydroxychloroquine Tablets - FDA prescribing information..

    It is well known that isolated lesions of chronic discoid lupus erythematosus may be treated by various local applications, e.g. various acids, solid carbon dioxide, and the intralesional injection of gold compounds. 2,3 Recently, we became interested in the report of Ottolenghi-Lodigiani, 4 on the combined intralesional and oral. Br Med J. 1955 Feb 5;14909329-30. Chloroquine sulphate in treatment of chronic discoid lupus erythematosus. LEWIS HJ. PMCID PMC2060911 Discoid Lupus Erythematosus of the Eyelids Harvey Siy Uy, MD Introduction Discoid lupus erythematosus DLE is a benign, autoimmune disorder of the skin. While the face, trunk and extremities are frequently affected, eyelid involvement is uncommon and often presents as a diagnostic problem.

  5. Aikipskov Well-Known Member

    Optic neuritis occurs when swelling (inflammation) damages the optic nerve — a bundle of nerve fibers that transmits visual information from your eye to your brain. Vitamin B12 Deficiency Optic Neuropathy a Teaching Case Report The. Methotrexate-induced optic neuropathy Request PDF Medications that can Affect the Eye or Visual System
  6. Aleksandr Well-Known Member

    Aralen Chloroquine - Action And Clinical Pharmacology Chloroquine has been found to be highly active against the erythrocytic forms of Plasmodium vivax, ovale and malariae and many strains of Plasmodium falciparum but not the gametocytes of Plasmodium falciparum. The precise mechanism of plasmodicidal action of the drug is not known.

    Aralen Chloroquine Uses, Dosage, Side Effects.