Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine for yeast Sle and plaquenil Find information about common, infrequent and rare side effects of Plaquenil Oral. The typical dose for hydroxychloroquine is 200-400mg per day and is based on a person’s body weight or if you are overweight, your ideal body weight. While hydroxychloroquine is considered a relatively safe medication, like all medications there are potential risks. I completely agree with Lynnwood that plaquenil helps stop the progression of your disease, so the longer you wait the worse your Sjogren's becomes. Plaquenil is a fairly benign medication and was originally developed to protect against malaria. Later it was found to help autoimmune diseases. It can be months before you get relief with plaquenil. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. More energy on plaquenil Plaquenil Uses, Dosage & Side Effects -, Ask the Expert Plaquenil and Sjögren’s Plaquenil toenailsOrder aralen prescribingPlaquenil for treatment of igg4 related disease Damage to the retina, the light sensitive portion of the inner eye, can occur with long-term use of Plaquenil or chloroquine Aralen. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Treatment/Plaquenil -. Plaquenil - FDA prescribing information, side effects and uses. If lupus fatigue is a problem for you, here are ways you can try to increase your energy while living with lupus. Skip to main content. If you have lupus you may need even more sleep. Body aches increased often after eating. Very painful headaches during the day & at night headlights of other cars were unbearable. Days just stuck in bed. One day of Plaquenil changed my life - it gave me more energy, eliminated the headaches, subsided inflammation/swelling, nearly non-existent pain! Three months later still going strong. OMG, I am experiencing this since doubling my Plaquenil dose just over a week ago, and am spending my days close to the toilet But honestly, I have a bit more energy and less joint pain. I am hoping the rumbly tumbly eases up soon! I am really grateful to have more than one toilet in the house! yikes.