Please review the following URL and make sure that it is spelled correctly. May 23, 2005 Birmingham, AL - Starting the antimalarial drug hydroxychloroquine (HCQ) (Plaquenil) early on in the disease process may help prevent damage accrual in patients with systemic lupus erythematosus (SLE) [ 1 ]. Ra plaquenil Plaquenil side effects back pain Despite widespread clinical use of antimalarial drugs such as hydroxychloroquine and chloroquine in the treatment of rheumatoid arthritis RA, systemic lupus erythematosus SLE and other. To assess if hydroxychloroquine can delay renal damage development in lupus nephritis patients. Lupus nephritis patients n=256 from LUMINA n=635, a multiethnic cohort of African Americans, Hispanics and Caucasians, age ≥16 years, disease duration. The antimalarial hydroxychloroquine appears to protect against organ damage in patients with systemic lupus erythematosus, and the drug should be more widely prescribed in lupus, say US. "This study suggests that patients with mild disease who are treated with HCQ do better in the long run than patients who were not treated with HCQ," lead author of the study, Dr Barri Fessler (University of Alabama at Birmingham Health System), tells rheuma wire . A new study, published in the May 2005 issue of Arthritis & Rheumatism, has demonstrated that HCQ appears to reduce the risk of damage accrual, provided the drug is initiated before damage has begun. Hydroxychloroquine for lupus epocrates Hydroxychloroquine DermNet NZ, Protective Effect of Hydroxychloroquine on Renal Damage in Patients. Generic of plaquenil and dryness People with systemic lupus erythematosus SLE who stop treatment with hydroxychloroquine less than 12 months after its start are at a higher risk of flares than those who continue using it for at least one year, a study suggests. The research, "Outcomes of Systemic Lupus Erythematosus in. Lupus Patients on Hydroxychloroquine for Less Than 1 Year.. Hydroxychloroquine in SLE. Hydroxychloroquine Oral Route Description and Brand Names - Mayo Clinic. Hydroxychloroquine is used for its effect on systemic lupus erythematosus SLE disease activity and long-term benefits. This can be limited by adherence. One way to assess adherence is to measure blood levels. Conflicting data exist regarding blood levels. In 1941, discoid lupus patients were treated successfully with Atabrine, a compound developed in Germany in the 1920s. In the mid-1940s, both hydroxychloroquine HCQ and chloroquine CQ had been synthesized. In 1955 HCQ was shown to be effective for both systemic lupus and rheumatoid arthritis. Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away.