Just google does low dose naltrexone cause a herxheimer's reaction and I am sure you will find a lot of info. Did you have your med compounded from pure naltrexone powder or from ground up 50 mg Revia/generic equivalent? Here is how it applies to AP https://en.wikipedia.org/wiki/Type_III_hypersensitivity https://chronicillnessrecovery.org/index.php? Hi, Boise CGM- Can you please describe the "awful"? Happy to help if you can provide a few key details. Who can prescribe plaquenil Chloroquine treats Plaquenil and puffy face Chloroquine and anti-kell Hi Guys, I haven't been here for a while - just checked in and found this question on Plaquenil - for me it took approx nine weeks to begin to work - I'm only taking 200mg per day so far - it seemed to stop working a few weeks later - most days are pretty good I s'pose but I drop nearly every afternoon. User Reviews for Hydroxychloroquine to treat Undifferentiated Connective Tissue Disease. Also known as Plaquenil, Quineprox. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare. Mar 14, 2017 I do believe that this is a herxing type reaction. I stayed very hydrated yesterday, and took 1500mg of L-glutamine last night before bed along with tylenol and my 1.5 mg of LDN. Wow, what a difference! I slept well, had none of the extreme swelling and pain that I did have the night and day before, and today I feel pretty good! He's excellent, open-minded, and in my opinion quite brilliant - and had the following comment when I asked him about LDN in an email. Kk I've quoted my scleroderma specialist on LDN here before, but will copy and paste it again. Will i feel worse before i feel better on plaquenil Plaquenil Reviews & Ratings at, User Reviews for Hydroxychloroquine to treat. - Quinine plaquenil Hydroxychloroquine received an overall rating of 7 out of 10 stars from 368 reviews. See what others have said about Hydroxychloroquine, including the effectiveness, ease of use and side effects. Hydroxychloroquine Reviews Everyday Health. LDN. can you feel worse before you get better.. Plaquenil - How long to take effect?. Sep 19, 2010 I do remember it took about 8 weeks before I noticed any difference at all. At three months I saw a big difference, and after six months, I am see a lot of difference. Before taking Plaquenil, I could barely walk. Everyone is different, so if a med is making you feel worse, I think you should let your doctor know and consider trying something else. I could no longer afford to see him or the other specialists I was seeing. The worst effect that I am aware of is the fact that my teeth have gotten progressively worse and keep breaking off at the gum line. I don't know whether it's the plaquenil or not, but my hair became really wavy and I had always had very straight hair before. F 61 2 years Got off of it and I feel back to normal. My Lupus is mild so I'm going the holistic route. Plant based diet, acupuncture, juicing. I feel good and will take minor aches and fatigue any day than being on plaquenil. Beware! Do your research before accepting a lab created Rx from Dr.s.