Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine itch mouse behavior I c hydroxychloroquine hsdd Plaquenil 200mg qd Hydroxychloroquine comes in an oral tablet. Adult dosing ranges from 200 mg or 400 mg per day 6.5mg/kg. In some cases, higher doses can be used. It is recommended one tablet twice daily if taking more than one tablet. It is recommended to be taken with food. For treating lupus in adults, the recommended starting Plaquenil dosage is 400 mg once or twice a day. After a while, your healthcare provider may recommend a lower dosage such as 200 mg once daily. The higher the long-term dosage, the more likely that serious Plaquenil side effects especially eye damage may occur. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side effects may require temporary reduction of Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil 200 mg daily Hydroxychloroquine Oral Uses, Side Effects, Interactions., Taking Plaquenil for Various Conditions and Treatment Tips Improvement of ra with hydroxychloroquine One PLAQUENIL tablet contains 200 mg of hydroxychloroquine sulfate, which is equivalent to 155 mg base. Take PLAQUENIL with a meal or a glass of milk. Malaria Prophylaxis. Adults. 400 mg 310 mg base once weekly on the same day of each week starting 2 weeks prior to exposure, and continued for 4 weeks after leaving the endemic area. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Plaquenil Dosage Guide -. Plaquenil - Side Effects, Uses, Dosage, Overdose.. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. To treat lupus erythematosus, the average adult dose is 400 mg once or twice daily. Jan 01, 2020 One Plaquenil tablet contains 200 mg of hydroxychloroquine sulfate, which is equivalent to 155 mg base. Take Plaquenil with a meal or a glass of milk. Malaria. Prophylaxis Adults 400 mg 310 mg base once weekly on the same day of each week starting 2 weeks prior to exposure, and continued for 4 weeks after leaving the endemic area. Hydroxychloroquine Tablets - Clinical Pharmacology. Pharmacokinetics. Following a single 200 mg oral dose of hydroxychloroquine sulfate to healthy males, the mean peak blood concentration of hydroxychloroquine was 129.6 ng/mL, reached in 3.26 hours with a half-life of 537 hours 22.4 days.