Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Primary care prescribe plaquenil Chloroquine resistant salmonella In the treatment of SLE, Plaquenil is widely regarded as a cornerstone drug in the management of skin & arthritis symptoms. History of Antimalarials The history of antimalarials dates back to the 1630s in Peru, where, in all likelihood, malaria was not endemic, and an extract from the “fever tree,” which grew on the eastern slopes of the Andes. In 1984, I wrote my first prescription for the antimalarial drug, hydroxychloroquine Plaquenil, for a 28-year-old woman with SLE. She was considerably overweight, with inflammatory arthritis and a photosensitive rash, and I worried that oral corticosteroids would tip her over into diabetes. To make sure Plaquenil is safe for you, tell your doctor if you have a history of vision changes or damage to your retina caused by an anti-malaria medication; heart disease, heart rhythm disorder such as long QT syndrome; diabetes; a stomach disorder; an allergy to quinine; liver or kidney. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. History of plaquenil Chloroquine - Wikipedia, Plaquenil From Malaria Treatment to Managing Lupus, RA - The. Plaquenil treats what symptoms does Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Uses, Dosage & Side Effects -. Drug spotlight on hydroxychloroquine Lupus Foundation of.. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine Plaquenil. This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day 200 bid. Highlights for hydroxychloroquine. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2.