For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. Plaquenil causing hearing loss Hydroxychloroquine pill identification 347 The mechanism of action is thought to be anti-inflammatory, but Plaquenil also seems to reduce sensitivity to sunlight. It has also been noted recently that smoking reduces the effectiveness of Plaquenil in treating lupus, thus, smoking cessation should be instituted in all patients taking Plaquenil. More About Autoimmune diseases DERMATOMYOSITIS Amyopathic dermatomyositis ADM is a variant of dermatomyositis DM lacking myopathy. Though it has been argued that patients with ADM are in a “premyopathic stage” of DM, several studies show that a minority of patients with ADM develop myopathy.1-3 Failure to recognize ADM may lead to inadequate. For most people, there’s no cure for dermatomyositis. Treatment can improve the condition of your skin and muscle weakness. Available treatments include medication, physical therapy, and surgery. A health care provider may consider these conditions in the table below when making a diagnosis. This information comes from a database called the Human Phenotype Ontology (HPO) Related diseases are conditions that have similar signs and symptoms. Plaquenil for amyopathic dermatomyositis Myositis skin disease and treatment The Myositis Association, Antimalarial Myopathy in Amyopathic Dermatomyositis. Stopping hydroxychloroquine sulfate tabsPlaquenil drug nutrient interactionsChloroquine resistance malaria cdcNeurontin and plaquenil interactions Plaquenil hydroxychloroquine "I've been taking Plaquenil since May 2008 for Dermatomyositis and rheumatoid arthritis. It's been great! It helped greatly with the fatigue. Highly recommended." Hydroxychloroquine User Reviews for Dermatomyositis at. Dermatomyositis Causes, Symptoms, and Treatment. PLAQUENIL Side Effects, Reviews by Patients page 3.. Amyopathic Dermatomyositis ADM and Hypomyopathic Dermatomyositis HDM, together referred to as Clinically Amyopathic Dermatomyositis CADM, are subsets of Dermatomyositis DM, one of the Idiopathic Inflammatory Myopathies. The cause is unclear and there is no cure. Amyopathic Dermatomyositis Less Benign than We Believed. The clinical phenotype of melanoma differentiation associated protein 5 MDA-5 dermatomyositis represents an overlap of a severe form of vasculopathy and rapidly progressive ILD. In clinically-amyopathic dermatomyositis, the skin rash can be present for long periods of time six months or longer without the appearance of muscle weakness some patients having dermatomyositis skin disease been observed to go 20 years or longer without developing muscle weakness.