What is the difference between chloroquine and chloroquine phosphate

Discussion in 'Cheap Chloroquine' started by Super-Puper, 19-Mar-2020.

  1. tonikas Guest

    What is the difference between chloroquine and chloroquine phosphate


    In certain countries and parts of the world where malaria is still present, a person can easily catch malaria from a seemingly insignificant mosquito bite. These medications are primarily designed to treat the strains of malaria linked with mosquito bites, but there are a few alternate uses for these medications outside the scope of treating malaria infections.

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    There is no real difference, but you need to dose less with chloroquine sulfate, since the substance has less molecular weight. A good approximation is that if you would dose 10 mg/l chloroquine phosphate you can dose 8.5 mg/l chloroquine sulfate instead. Also CP does not need to be 99% pure to be effective. The mechanism of chloroquine and hydroxychloroquine toxicity is not well understood. Chloroquine has an affinity for pigmented melanin-containing structures, which may explain its toxic properties in the eye. Melanin serves as a free-radical stabilizer and can bind toxins, including retinotoxic drugs. Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase.

    It belongs to a disease-modifying antirheumatic drug classification. Combined with other medications, hydroxychloroquine is often used as part of a treatment plan for a host of auto-immune diseases, such as rheumatoid arthritis and lupus.

    What is the difference between chloroquine and chloroquine phosphate

    Chloroquine Phosphate - WebMD, Chloroquine and Hydroxychloroquine Toxicity Practice.

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  5. Just in case you are late to the party, Chinese scientists have discovered an antiviral drug that has curative effects on the Corona virus epidemic. Yes, for real. You will not believe who the star of this party is an all time favourite of Nigerian parents and doctors, Chloroquine. Chloroquine has been found to have positive effects on patients of the virus.

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    There was however a difference in the depth of itch after utilizing chloroquine in malaria therapy. Enzyme deficiency corresponding to glucose-6-phosphate dehydrogenase has been discovered to be comparatively extra frequent amongst itchers than non-itchers. Jul 02, 2007 For chloroquine, the quinoline ring was positioned between W183 and Y234 and the tertiary ammonium stabilised by interactions with F226. Conclusions and Implications This study shows that quinine and chloroquine competitively inhibit 5-HT 3 receptors, while mefloquine inhibits predominantly non-competitively. Oct 01, 2018 Chloroquine phosphate tablets, Chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble inwater. Chloroquine phosphate tablets are an antimalarial and amebicidal drug.

     
  6. OledJ Guest

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. How Lupus Affects the Nervous System Johns Hopkins Management of Neuropsychiatric Systemic Lupus. Plaquenil
     
  7. CCM_SNIPER Moderator

    Hydroxychloroquine Plaquenil Toxicity and Recommendations. Aug 30, 2011 She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to presentation. Past Ocular History None

    Plaquenil-Induced Toxic Maculopathy - Decision-Maker PLUS