Chloroquine resistance in myanmar

Discussion in 'Cheap Chloroquine' started by Sergio20, 10-Mar-2020.

  1. pplayer1981 Guest

    Chloroquine resistance in myanmar


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    The porous border with Myanmar could be one of the major entry routes of drug-resistant parasites to mainland India. In 1973, the first cases of P. falciparum chloroquine resistance CQR were reported from Karbi Anglong district in Assam 5. In the early 1980s, CQR was reported in Mizoram 6. Clearly, chloroquine was losing its efficacy because 13% of P. vivax isolates taken from Myanmar-Thailand border between 20 demonstrated a resistance to chloroquine. It was likely that the emergence and spread of chloroquine resistance of P. vivax MDR malaria parasites occurred in the early 2000s across the country. All the chloroquine-resistant cases were again treated with chloroquine 1500 mg and no further recrudescence or relapse was detected on days 21 and 28. This study indicates that chloroquine is losing its efficacy against P. vivax in Myanmar.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine resistance in myanmar

    Malaria on Myanmar-India border is 'huge threat' - BBC News, Border Malaria Associated with Multidrug Resistance on Thailand-Myanmar.

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  6. Jun 25, 2013 Between 20, Guthmann et al. reported chloroquine resistance in Dawei Mon State, Myanmar, by conducting an in vivo susceptibility study using WHO standard treatment protocol for P. vivax 10 mg/kg over the first 2 days and 5 mg/kg on day 3, for adult patients. A 34% recurrence of parasitemias was likely to have delayed parasite clearance times as was treatment failures with chloroquine.

    • Border Malaria Associated with Multidrug Resistance on..
    • Development of resistance to chloroquine by Plasmodium vivax in Myanmar..
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    QUESTION In India how to treat a child and adult suffering from malaria? ANSWER Chloroquine-resistant malaria has been observed in India and so the first line drug of choice should be an artemisinin-derivative in combination with another drug this group of medications are more generally known as "artemisinin-based combination therapies" or ACTs. Spread of artemisinin-resistant Plasmodium falciparum in Myanmar a cross-sectional survey of the K13 molecular marker February 21, 2015 By Leave a Comment Emergence of artemisinin resistance in southeast Asia poses a serious threat to the global control of Plasmodium falciparum malaria. Malaria. Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. ovale, and P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine has been extensively used in mass drug administrations.

     
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