It improves anemia and parasite level in the blood for the pregnant women and the birthweight in their infants. Recent improvements in malaria prevention strategies have further enhanced its effectiveness in combating areas highly infected with the malaria parasite. Proguanil plus chloroquine Drug interaction of chloroquine Sulfasalazine vs hydroxychloroquine To determine the effect of chloroquine chemoprophylaxis during pregnancy on birth weights, a randomized trial was carried out in 19 in Banfora, Burkina Faso West Africa. Usual Adult Dose for Malaria Prophylaxis. 500 mg chloroquine phosphate 300 mg base orally on the same day each week Comments-If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate 600 mg base may be taken orally in 2 divided doses, 6 hours apart. Chloroquine is the drug of choice in the few malaria-endemic areas free of CRPf. Combining chloroquine and proguanil is an option for CRPf when other first-line antimalarials are contraindicated. Dosage should be calculated in terms of the base. The adult chloroquine dose is 300 mg base weekly or in some countries 100 mg base daily. This form of mosquito repellent is slowly replacing indoor residual spraying, which is considered to have high levels of toxicity by WHO (World Health Organization). Additional bite prevention measures include mosquito and insect repellents that can be directly applied to skin. Chloroquine chemoprophylaxis Aralen Chloroquine Uses, Dosage, Side Effects., Chloroquine Dosage Guide with Precautions - Chloroquine side effects long termHow plaquenil worksPlaquenil hydroxychloraquine doseageChloroquine phosphate suspension ip in hindi Chloroquine administered as intermittent therapy did not provide better protection from malaria and related adverse effects compared with intermittent sulfadoxine-pyrimethamine in a setting of high resistance to sulfadoxine-pyrimethamine. Chloroquine chemoprophylaxis might provide benefit in protecting against malaria during pregnancy, but studies with larger sample sizes are needed to confirm. Chloroquine as weekly chemoprophylaxis or intermittent.. Chloroquine - an overview ScienceDirect Topics. Tolerability of doxycycline monohydrate salt vs.. Chloroquine phosphate tablets, Chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble inwater. Chloroquine phosphate tablets are an antimalarial and amebicidal drug. However, CATMAT considers chloroquine-proguanil chemoprophylaxis to be significantly less effective compared with atovaquone-proguanil, doxycycline or mefloquine Reference 26, Reference 27 and does not recommend this regimen. When chloroquine, doxycycline, or mefloquine is used for primary prophylaxis, primaquine is usually taken during the last 2 weeks of postexposure prophylaxis. When atovaquone-proguanil is used for prophylaxis, primaquine may be taken during the final 7 days of atovaquone-proguanil, and then for an additional 7 days.