Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Chloroquine otc Does plaquenil Hydroxychloroquine for low platelets Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Despite cessation of hydroxychloroquine, one-year follow-up revealed a mild worsening visual acuity to 20/30 OD and 20/25 OS, with new abnormalities on Amsler grid and deficits on color vision testing. Feb 19, 2020 Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Visual defects hydroxychloroquine How to interpret visual fields 5 most common patterns - EyeGuru, Hydroxychloroquine Plaquenil Toxicity and Recommendations. Plaquenil and celebrex Background/Aims Hydroxychloroquine HCQ retinopathy may result in severe and irreversible vision loss, emphasising the importance of screening and early detection. The purpose of this study is to report the novel finding of early optical coherence tomography OCT abnormalities due to HCQ toxicity that may develop in the setting of normal Humphrey visual field HVF testing. Early hydroxychloroquine retinopathy optical coherence.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Toxic Retinopathy With Hydroxychloroquine Therapy - JAMA. Patients with persistent and significant visual field defects consistent with hydroxychloroquine retinopathy, but without evidence of structural defects on SD-OCT or FAF may be considered for multifocal electronicretinography. D. Visual field defects Pericentral or paracentral scotoma, central scotoma with decreased visual acuity, rarely field constriction. The most common visual symptoms attributed to the retinopathy are reading and seeing difficulties words, letters, or parts of objects missing, photophobia, blurred distance vision, missing or blacked out areas in the central or peripheral visual field, light flashes and streaks. Chloroquine retinopathy, is a form of toxic retinopathy damage of the retina caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs.