I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Plaquenil for sle Medication for rheumatoid arthritis plaquenil Hydroxychloroquine comes as a tablet to take by mouth. For prevention of malaria in adults, two tablets are usually taken once a week on exactly the same day of each week. The first dose is taken 1 to 2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks after exposure. Aug 26, 2016 So I ran out of my plaquenil and the Rheum. that prescribed it I am no longer seeing and wont re-fill it and I dont see my new Rheum. until Decemeber 23rd. I am nervous to see what will happen. The pharmacist said there wont be any danger just stopping it. Im just nervous to see what my body will do. Has anyone gone off the plaquenil and what happened? I hear my new Rheum. is all for it so I. For patients taking hydroxychloroquine to prevent malaria Your doctor may want you to start taking this medicine 1 to 2 weeks before you travel to an area where there is a chance of getting malaria. This will help you to see how you react to the medicine. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. Tapering hydroxychloroquine SARCOIDOSIS TREATMENT GUIDELINES, Stopping Plaquenil - General Discussion - Life With Lupus Hydroxychloroquine side effects mayo clinicPlaquenil make tongue starchyPlaquenil visualf iedlPlaquenil eye effects Happily, going off plaquenil quelled the worst of my psoriasis, so the overall trade-off was eventually worth it for me. It wasn't very clear from your post whether it was the primary care doctor or the rheumatologist who wants him to decrease the plaquenil. Going off Plaquenil - Sclero Forums MAIN - Sclero Forums. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Let me tell you what weaning down from Plaquenil is like.. Hydroxychloroquine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or. With the Plaquenil I don't think you will find much relief in such a short time on it & at half of a workable dose. I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage.