It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Side effect of plaquenil on eyes Does plaquenil cause hair growth It is not necessary to withdraw an antimalarial drug during pregnancy if the rheumatic disease is well controlled; however, the manufacturer of hydroxychloroquine advises avoiding use. Breast feeding Avoid—risk of toxicity in infant. Objective. To investigate the effect of hydroxychloroquine HCQ in pregnant women with systemic lupus erythematosus SLE. Methods. In SLE pregnancies of a single Dutch center 2000–2015, lupus activity and flares before and during pregnancy and postpartum were assessed using the SLE Disease Activity Index SLEDAI/SLEPDAI SLEDAI adjusted for pregnancy. Hydroxychloroquine HCQ is often needed to manage disease activity in systemic lupus erythematosus SLE during pregnancy. The purpose of this study was to examine lupus activity and pregnancy outcomes in women with SLE treated or not treated with HCQ during pregnancy. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Pregnancy hydroxychloroquine Plaquenil and Pregnancy - Antibiotics Home Page, Hydroxychloroquine Use in Lupus Patients during Pregnancy. Chloroquine and primaquine us militaryPlaquenil usual dosageHow often do you need labs on plaquenil OBJECTIVE The use of hydroxychloroquine HCQ in pregnancy remains controversial. The recent demonstration that HCQ passes across the placenta, with cord blood concentrations nearly identical to those found in maternal blood, emphasizes the need for careful evaluation of pregnancies in women receiving HCQ. Safety of hydroxychloroquine in pregnant patients with.. Hydroxychloroquine in lupus pregnancy - Clowse - 2006.. Hydroxychloroquine Use During Pregnancy. The role of hydroxychloroquine HCQ for achieving this control is now recognized. Several studies demonstrate that patients with SLE who continue HCQ during pregnancy have decreased flares and improved pregnancy outcomes, including longer fetal gestation and infants with higher birth weight3,4. Stars. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. May 13, 2009 The anti-malarial drugs Hydroxychloroquine HCQ is widely used to treat various rheumatic diseases mechanism of action of this drug is to increase the pH in acidic vesicles, inhibiting receptor mediated endocytosis that affects many cellular functions including antigen presentation, toll receptor signaling and post-transcriptional modification of proteins 2–4.