Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine in vivo Dangers of plaquenil in half Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Here are 8 weight loss tips that you can ignore. Plaquenil and Weight loss - a study from real-world data. Summary Weight loss is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil losing weight Does Plaquenil hydroxychloroquine cause weight loss ? I., Will you have Weight loss with Plaquenil - eHealthMe Methotrexate and folic acid and plaquenil Weight based dosage in adults and pediatric patients 13 mg/kg 10 mg/kg base, not to exceed 800 mg 620 mg base followed by 6.5 mg/kg 5 mg/kg base, not to exceed 400 mg 310 mg base, at 6 hours, 24 hours and 48 hours after the initial dose. PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. Plaquenil Dosage Guide -. Plaquenil Risk Calculators. Plaquenil and weight gain -. Just wondering if anyone else had problems with loss of appetite and weight loss while on plaquenil. I had my dose increased to 400mg a day about three weeks ago, and since then I have no appetite whatsoever. Weight is falling off me at a rather alarming rate - at least half a stone a week. The diarrhea stopped and I am still dropping the weight. But the weight loss didn't start until I refilled my new prescription for plaquenil. I've heard before that plaquenil causes weight loss. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects.