Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Lc3-ii vs lc3-i ratio chloroquine Plaquenil dosage for lyme disease Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong. Skin discoloration - bluish in Plaquenil - how severe and when it was recovered? Summary We study how severe was Skin discoloration - bluish, when it was recovered, drug effectiveness, race, and more among people who take Plaquenil. This study is created by eHealthMe based on reports of 1,993 people who have side effects when taking Plaquenil. Drug-induced skin pigmentation can become cosmetically disfiguring. In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil skin discoloration Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Skin discoloration - bluish in Plaquenil how severe and. Medication for rheumatoid arthritis instead of plaquenil Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Drug-induced hyperpigmentation DermNet NZ. Hydroxychloroquine-induced Hyperpigmentation of the Skin.. Hydroxychloroquine pigmentation can occur within 1 year after starting therapy 4, 12, 13, 17. The skin discoloration has no systemic adverse sequelae. After discontinuation of the drug, the hydroxychloroquine-associated pigmentation slowly fades. Hi i have sd there are skin problems that comes with sd dont know if u have that and i also have raynauds.i have been on plaquinil for years and i have skin irritations but was told by doctors its from the sd.u may want to ask ur doc about that but i do no most sd sufferers have skin probs.u have scleroderma? I was diagnosed almost 2yrs ago with Lupus, SLE & subacute subcutaneous. The plaquenil made me lose my hair immediately. When it came back in most of it came in white which I read that the medicine can bleach your hair. Then last year I noticed areas on my legs that are brown or maybe it's that my skin has been bleached in areas and is very white.