I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Plaquenil for ankylosing spondylitis Taking plaquenil and hands still swollen Hydroxychloroquine sulfate overdose Malaria dominican republic chloroquine resistance If you don't have to, don't stop your plaquenil. I stopped taking the plaquenil the beginning of December. It doesn't agree with my stomach I take it with meals too. And since I hadn't had a miraculous recovery the 6 months I'd been on it, I didn't think there was any harm in stopping it. What will happen if you stop taking plaquenil? Wiki User November 17, 2011 PM. I was wondering what would happen when you stop taking plaquenil after trying it out for 3- 6 months. Some patients decide to stop taking statins, a cholesterol-lowering drug, if they experience side effects. A new study tracked how they did. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. What will happen if i stop taking plaquenil Plaquenil Oral Uses, Side Effects, Interactions., What will happen if you stop taking plaquenil - Answers Chloroquine phosphate and pregnancyTongue swelling from plaquenilDoes plaquenil cause heat intolerance Finally, my rheumatologist recommended that I stop taking the drug altogether.” Utterback’s rheumatologist also referred her to neuro-ophthalmologist David Katz, MD, in Bethesda, Md. “We don’t know which patients might develop Plaquenil retinopathy, but the patient often can see it before the doctor can,” he says. Protecting your eyesight when taking Plaquenil Lupus.. Statins What happens to patients who stop taking them.. Plaquenil and the sun - Sarcoidosis - Inspire. It's ok to stop plaquenil without weaning, but I do recommend that if you feel you can wait til Monday, wait, and talk with your rheumy then. I felt that plaquenil wasn't helping, and was causing digestive problems for me, so with my dr. ok, I went off it. After two weeks off, I discovered it had been doing some good on the joint and muscle pain. I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few months, but it can take up to six months for full effects. Stop taking the medicine and.