In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Chloroquine failure deaths in africa Mechanism of chloroquine action Hydroxychloroquine originally used to treat User Reviews for Hydroxychloroquine to treat Sjogren's Syndrome. If your are wondering how long the plaquenil takes to work, it took about 3 months before I starting feeling better. Now at 6 months I’m noticing more symptoms. I have a rash on my arms and my face feels like it’s burning but I don’t have a sunburn or anything. And why is plaquenil unlikely to work according to your rheumy? July 1, 2017, pm #3. Hello, the rheumy said that research has showed that plaquenil does not work. I can take exovac for few days and then it ceases to help and I’m dryer than before. symptoms of the Sjogren’s, I had the flu for the very first time of my It’s used in people with Sjogren’s syndrome, rheumatoid arthritis, and lupus to relieve joint pain, fatigue, and rashes. It may take up to 12 weeks for you to notice the effects of hydroxychloroquine. Hydroxychloroquine is safe, even for pregnant women with Sjogren’s syndrome. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. How does plaquenil work for sjogren& 39 Why There's More to Sjogren's Syndrome The Dr. Oz Show, Sjogrens and hormones - General - Sjogren's Syndrome Support Best price hydroxychloroquinePlaquenil and hpvHigh cost of hydroxychloroquineRetinopathy symptoms from plaquenilIs plaquenil used to treat osteoarthritis My rheumy thinks in the long run plaquenil will not be enough for me and I will have to go to the next step. My question is, if plaquenil doesn't work, what is the next step of medication? Rheumy is very conservative with meds and always looks for the smallest dose possible and the least amount of meds. What step comes after plaquenil? - Sjogren's World. Medications for Sjogren’s Syndrome NYU Langone Health. Diagnosis of Sjögren's Syndrome Johns Hopkins Sjögren’s.. I "know" I need some meds, but cannot tolerate Plaquenil. Wondering if anyone has come across something "natural" that mimics it. Thanks & LIGHT*****carole - Hi, Carole. When I started Plaquenil, my GI system was in an uproar. But it usually was anyway. I didn't realize, until I saw Dr. All information contained within the Johns Hopkins Lupus Center website is intended for educational purposes only. Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained within this site. The short answer is that nobody really knows how or why Plaquenil helps autoimmune diseases- they just know it does. It was discovered by accident - it's an anti-malarial drug, and doctors noticed that while being treated for malaria, patients with Rheumatoid autoimmune conditions had spontaneous improvement of symptoms.